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DeCS
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Descritor Inglês:
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Forkhead Box Protein L2
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Descritor Espanhol:
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proteína forkhead box L2
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Descritor Português:
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Proteína Forkhead Box L2
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Sinônimos Inglês:
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FOXL2 Protein
Forkhead Box L2 Protein
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Categoria:
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D12.776.260.950.249.032
D12.776.930.977.249.032
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Definição Inglês:
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A forkhead box transcription factor that is expressed in the developing eyelid and during very early development of the gonad, prior to sex determination. It is essential for development of the ovary and inhibits SOX9 TRANSCRIPTION FACTOR to prevent differentiation to testes. It also induces APOPTOSIS in ovarian cells. Mutations in the FOXL2 gene are associated with BLEPHAROPHIMOSIS; Ptosis, and Epicanthus inversus (BPES with ovarian failure). |
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Nota Histórica Inglês:
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2018
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Qualificadores Permitidos Inglês:
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Número do Registro:
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57121
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Identificador Único:
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D000074842
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Ocorrência na BVS:
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Similar:
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DeCS
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