Pesquisa sobre:
MFN=57573
Descritores Encontrados:
1
Mostrando:
1 .. 1
1 / 1
DeCS
Descritor
Inglês
:
Exenatide
Descritor
Espanhol
:
exenatida
Descritor
Português
:
Exenatida
Sinônimos
Inglês
:
AC 2993
AC 2993 LAR
Bydureon
Byetta
Ex4 Peptide
Exendin 4
Exendin-4
ITCA 650
Peptide, Ex4
Categoria:
D12.644.187
D20.888.300
D23.946.833.300
Definição
Inglês
:
A synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the Gila monster lizard (
Heloderma suspectum
).
Exenatide
increases
CYCLIC AMP
levels in pancreatic
acinar cells
and acts as a
GLUCAGON-LIKE PEPTIDE-1 RECEPTOR
(GLP-1) agonist and incretin mimetic, enhancing
insulin secretion
in response to increased
glucose
levels; it also suppresses inappropriate
glucagon
secretion and slows
gastric emptying
. It is used an anti-diabetic and anti-obesity agent.
Ação Farmacológica:
Hypoglycemic Agents
Anti-Obesity Agents
Incretins
Nota Histórica
Inglês
:
2019 (1992)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Número do Registro:
57573
Identificador Único:
D000077270
Ocorrência na BVS
:
Similar:
DeCS