Pesquisa sobre: MFN=57585 
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Descritor Inglês:   Abciximab 
Descritor Espanhol:   abciximab 
Descritor Português:   Abciximab 
Sinônimos Inglês:   CentoRx
Chimeric 7E3 Fab
Clotinab
Fab, Chimeric 7E3
ReoPro
c7E3 Fab  
Categoria:   D12.644.541.500.650.125
D12.776.124.486.485.114.224.060.125
D12.776.124.486.485.680.650.125
D12.776.124.790.651.114.224.060.125
D12.776.124.790.651.680.650.125
D12.776.377.715.548.114.224.200.125
D12.776.377.715.548.680.650.125
Definição Inglês:   A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting. 
Ação Farmacológica:   Anticoagulants
Platelet Aggregation Inhibitors
 
Nota Histórica Inglês:   2019 (1994) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   57585 
Identificador Único:   D000077284 

Ocorrência na BVS:
 

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