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DeCS
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Descriptor English:
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12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
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Descriptor Spanish:
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ácido 12-hidroxi-5,8,10-eicosatetraenoico
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Descriptor Portuguese:
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Ácido 12-Hidroxi-5,8,10,14-Eicosatetraenoico
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Synonyms English:
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12 S Hydroxyeicosatetraenoic Acid
12-HETE
12-R-HETE
12-S-HETE
12-S-Hydroxyeicosatetraenoic Acid
Acid, 12-S-Hydroxyeicosatetraenoic
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Tree Number:
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D10.251.355.255.100.300.425
D10.251.355.310.166.550.425
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Definition English:
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A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51) |
History Note English:
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97; was 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID (NM) 1975-96
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Allowable Qualifiers English:
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Record Number:
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32975
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Unique Identifier:
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D019377
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Occurrence in VHL:
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Similar:
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DeCS
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