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230 KDA BULLOUS PEMPHIGOID ANTIGEN
Descriptors Found:
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DeCS
Descriptor
English
:
Dystonin
Descriptor
Spanish
:
distonina
Descriptor
Portuguese
:
Distonina
Synonyms
English
:
230 240 kDa Bullous Pemphigoid Antigen
230 kDa Bullous Pemphigoid Antigen
230-240 kDa Bullous Pemphigoid Antigen
Bullous Pemphigoid Antigen 1
Hemidesmosomal Plaque Protein
Tree Number:
D12.776.220.790.625
Definition
English
:
A plakin characterized by repeat sequences homologous to
SPECTRIN
and
PLECTIN
and C-terminal
EF HAND MOTIFS
. It functions as an integrator of
INTERMEDIATE FILAMENTS
, ACTIN and
MICROTUBULES
in
cytoskeleton
networks. It is required for anchoring
intermediate filaments
to the
actin cytoskeleton
in neural and
muscle cells
as well as anchoring KERATIN-containing
intermediate filaments
to
HEMIDESMOSOMES
in
EPITHELIAL CELLS.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56594
Unique Identifier:
D000071821
Occurrence in VHL
:
Similar:
DeCS