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BECLIN 1 PROTEIN
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DeCS
Descriptor
English
:
Beclin-1
Descriptor
Spanish
:
beclina-1
Descriptor
Portuguese
:
Proteína Beclina-1
Synonyms
English
:
ATG 6 Protein
ATG-6 Protein
ATG6 Protein
Beclin 1
Beclin 1 Protein
Beclin-1 Protein
Beclin1
Coiled coil Myosin like Bcl2 interacting Protein
Coiled-coil Myosin-like Bcl2-interacting Protein
GT197 Protein
Tree Number:
D12.644.360.075.335
D12.776.094.500
D12.776.476.075.335
Definition
English
:
An
autophagy
related protein which functions as a core subunit of
PHOSPHATIDYLINOSITOL 3-KINASE
MULTIPROTEIN COMPLEXES
. It mediates the formation of phosphatidylinositol 3-phosphate and functions in
AUTOPHAGY
, where it is required for maturation of the
AUTOPHAGOSOME
. It also functions in
ENDOCYTOSIS
and
CYTOKINESIS
as part of a separate complex.
Beclin-1
associates with
INTRACELLULAR MEMBRANES
and interacts with the
PROTO-ONCOGENE PROTEINS C-BCL-2
and
BCL-X PROTEIN.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56546
Unique Identifier:
D000071186
Occurrence in VHL
:
Similar:
DeCS