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DeCS
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Descriptor English:
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Leukemia Inhibitory Factor Receptor alpha Subunit
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Descriptor Spanish:
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subunidad alfa del receptor del factor inhibidor de leucemia
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Descriptor Portuguese:
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Subunidade alfa de Receptor de Fator Inibidor de Leucemia
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Synonyms English:
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Antigen, CD118
Antigens, CD118
CD118 Antigen
CD118 Antigens
LIF Receptor alpha Subunit
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Tree Number:
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D12.776.543.750.705.852.583.750
D12.776.543.750.750.400.550.250.750
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Definition English:
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A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor for LEUKEMIA INHIBITORY FACTOR and ONCOSTATIN M. The subunit is also a component of the CILIARY NEUROTROPHIC FACTOR RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to ALTERNATIVE SPLICING of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor. |
History Note English:
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2007
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Allowable Qualifiers English:
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Record Number:
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52379
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Unique Identifier:
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D053680
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Occurrence in VHL:
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Similar:
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DeCS
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