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CL-67,772
Descriptors Found:
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DeCS
Descriptor
English
:
Amoxapine
Descriptor
Spanish
:
amoxapina
Descriptor
Portuguese
:
Amoxapina
Synonyms
English
:
2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine
Asendin
Asendis
CL 67,772
CL-67,772
CL67,772
Demolox
Desmethylloxapine
Défanyl
Tree Number:
D03.633.300.347.500.040
Definition
English
:
The N-demethylated derivative of the antipsychotic agent
LOXAPINE
that works by blocking the reuptake of
norepinephrine
,
serotonin
, or both; it also blocks
dopamine
receptors.
Amoxapine
is used for the treatment of
depression.
Pharmacological Action:
Antidepressive Agents, Tricyclic
Neurotransmitter Uptake Inhibitors
Serotonin Uptake Inhibitors
Dopamine Antagonists
Adrenergic Uptake Inhibitors
History Note
English
:
91(75); was see under DIBENZOXAZEPINES 1975-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
672
Unique Identifier:
D000657
Occurrence in VHL
:
Similar:
DeCS