Search on:
CASPASE-8
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Caspase 8
Descriptor
Spanish
:
caspasa 8
Descriptor
Portuguese
:
Caspase 8
Synonyms
English
:
CAP4 Protease
Caspase-8
FLICE Protein
MACH Protein
Mch5 Protease
Pro Caspase 8
Pro-Caspase-8
Procaspase 8
Procaspase-8
Tree Number:
D08.811.277.656.262.500.126.550.800
D08.811.277.656.300.200.126.550.800
D12.644.360.024.285.037
D12.644.360.075.405.550.800
D12.644.360.075.421.037
D12.776.157.057.018.037
D12.776.476.024.320.025
D12.776.476.075.405.550.800
D12.776.476.075.421.037
Definition
English
:
A long pro-domain caspase that contains a
death effector domain
in its pro-domain region.
Caspase 8
plays a role in
APOPTOSIS
by cleaving and activating
EFFECTOR CASPASES
. Activation of this enzyme can occur via the interaction of its N-terminal
death effector domain
with
DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS
.
Entry Combination - descr/qualif
English
:
Caspase 8
/
antagonists & inhibitors
use
Caspase Inhibitors
Caspase 8
/
deficiency
use
Alstrom Syndrome
See Related
English
:
Autoimmune Lymphoproliferative Syndrome
History Note
English
:
2007(2000)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52227
Unique Identifier:
D053181
Occurrence in VHL
:
Similar:
DeCS