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CATHEPSIN B LIKE PROTEINASE
Descriptors Found:
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DeCS
Descriptor
English
:
Cathepsin B
Descriptor
Spanish
:
catepsina B
Descriptor
Portuguese
:
Catepsina B
Synonyms
English
:
Cathepsin B Like Proteinase
Cathepsin B-Like Proteinase
Cathepsin B1
Proteinase, Cathepsin B-Like
Tree Number:
D08.811.277.656.224.125
D08.811.277.656.262.500.133
D08.811.277.656.300.200.133
Definition
English
:
A lysosomal
cysteine
proteinase with a specificity
similar
to that of
PAPAIN
. The enzyme is present in a variety of
tissues
and is important in many physiological and pathological processes. In
pathology
,
cathepsin B
has been found to be involved in DEMYELINATION;
EMPHYSEMA
;
RHEUMATOID ARTHRITIS
, and
NEOPLASM INVASIVENESS.
History Note
English
:
87
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23222
Unique Identifier:
D002401
Occurrence in VHL
:
Similar:
DeCS