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DeCS
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Descriptor English:
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Complement C5b
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Descriptor Spanish:
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complemento C5b
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Descriptor Portuguese:
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Complemento C5b
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Synonyms English:
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C5b Complement
C5b, Complement
Complement 5b
Complement Component 5b
Complement, C5b
Component 5b, Complement
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Tree Number:
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D12.776.124.486.274.450.625
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Definition English:
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The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX. |
Pharmacological Action:
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Immunologic Factors
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History Note English:
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2006 (1982)
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Allowable Qualifiers English:
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Record Number:
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50827
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Unique Identifier:
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D050776
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Occurrence in VHL:
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Similar:
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DeCS
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