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FIBROBLAST GROWTH FACTOR RECEPTOR 2B
Descriptors Found:
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DeCS
Descriptor
English
:
Receptor, Fibroblast Growth Factor, Type 2
Descriptor
Spanish
:
receptor tipo 2 de factor de crecimiento de fibroblastos
Descriptor
Portuguese
:
Receptor Tipo 2 de Fator de Crescimento de Fibroblastos
Synonyms
English
:
Antigen, CD332
BEK Fibroblast Growth Factor Receptor
BEK Fibroblast Growth Factor Receptor Kinase
BEK Protein Tyrosine Kinase
Bek Fgf Receptor Kinase
Bek Related Fibroblast Growth Factor Receptor 1
Bek-Related Fibroblast Growth Factor-Receptor-1
CD332 Antigen
FGFR2 Protein
FGFR2b
FGFR2c
Fibroblast Growth Factor Receptor 2
Fibroblast Growth Factor Receptor 2b
Fibroblast Growth Factor Receptor 2c
Fibroblast Growth Factor Receptors 2
Fibroblast Growth Factor Receptors 2b
Receptor, Fibroblast Growth Factor 2b
Receptor, Fibroblast Growth Factor 2c
Tree Number:
D08.811.913.696.620.682.725.400.178
D12.776.543.750.630.441
D12.776.543.750.750.400.370.750
Definition
English
:
A
fibroblast
growth
factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by
FIBROBLAST GROWTH FACTOR 2
. A second isoform is expressed mainly by
EPITHELIAL CELLS
and is activated by
FIBROBLAST GROWTH FACTOR 7
and
FIBROBLAST GROWTH FACTOR 10
.
Mutation
of the gene for
fibroblast
growth
factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT
SYNDROME
; and CROUZON
SYNDROME
).
See Related
English
:
Acrocephalosyndactylia
Antley-Bixler Syndrome Phenotype
Craniofacial Dysostosis
History Note
English
:
2006(1999)
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
50734
Unique Identifier:
D051497
Occurrence in VHL
:
Similar:
DeCS