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DeCS
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Descriptor English:
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Forkhead Box Protein O3
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Descriptor Spanish:
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proteína forkhead box O3
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Descriptor Portuguese:
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Proteína Forkhead Box O3
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Synonyms English:
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FOXO3 Protein
Forkhead in Rhabdomyosarcoma Like 1 Protein
Forkhead in Rhabdomyosarcoma-Like 1 Protein
Protein, FOXO3
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Tree Number:
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D12.776.260.950.249.125
D12.776.930.977.249.125
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Definition English:
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A forkhead box transcription factor and transcriptional activator which triggers type 1 programmed cell death (APOPTOSIS) in the absence of APOPTOSIS INHIBITING PROTEINS, including neuronal cell death induced by OXIDATIVE STRESS. It recognizes and binds to the DNA sequence 5'-(AG)TAAA(TC)A-3' and also functions in post-transcriptional regulation of the c-MYC PROTO-ONCOGENE. |
History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56615
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Unique Identifier:
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D000071316
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Occurrence in VHL:
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Similar:
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DeCS
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