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I-KAPPA B PROTEINS
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DeCS
Descriptor
English
:
I-kappa B Proteins
Descriptor
Spanish
:
Proteínas B I-kappa
Descriptor
Portuguese
:
Proteínas I-kappa B
Synonyms
English
:
I kappa B
I kappa B Proteins
I-kappa B
IkB DNA Binding Proteins
IkB DNA-Binding Proteins
Tree Number:
D12.644.360.365
D12.776.260.420
D12.776.476.381
D12.776.930.326
Definition
English
:
A
family
of inhibitory
proteins
which bind to the REL
PROTO-ONCOGENE PROTEINS
and modulate their activity. In the
CYTOPLASM
,
I-kappa B proteins
bind to the transcription factor
NF-KAPPA B
. Cell stimulation causes its dissociation and translocation of active
NF-kappa B
to the nucleus.
See Related
English
:
I-kappa B Kinase
NF-kappa B
Proto-Oncogene Proteins c-rel
History Note
English
:
2006(2000)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34471
Unique Identifier:
D020672
Occurrence in VHL
:
Similar:
DeCS