Search on:
METHYLDOPAHYDRAZINE
Descriptors Found:
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DeCS
Descriptor
English
:
Carbidopa
Descriptor
Spanish
:
carbidopa
Descriptor
Portuguese
:
Carbidopa
Synonyms
English
:
Carbidopa, (R)-Isomer
Carbidopa, (S)-Isomer
Lodosin
Lodosyn
MK 485
MK 486
MK-485
MK-486
MK485
MK486
Methyldopahydrazine
Tree Number:
D02.092.311.200.538.200
D02.442.200
D02.455.426.559.389.657.166.175.200.538.200
Definition
English
:
An inhibitor of
DOPA DECARBOXYLASE
that prevents conversion of
LEVODOPA
to
dopamine
. It is used in
PARKINSON DISEASE
to reduce peripheral adverse effects of
LEVODOPA
. It has no anti-parkinson activity by itself.
Pharmacological Action:
Antiparkinson Agents
Dopamine Agents
Aromatic Amino Acid Decarboxylase Inhibitors
History Note
English
:
80; was METHYLDOPAHYDRAZINE see under HYDRAZINES 1975-79; was METHYLDOPAHYDRAZINE 1973-74 (Prov)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23960
Unique Identifier:
D002230
Occurrence in VHL
:
Similar:
DeCS