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DeCS
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Descriptor English:
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Phorbol 12,13-Dibutyrate
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Descriptor Spanish:
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forbol 12,13-dibutirato
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Descriptor Portuguese:
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Dibutirato de 12,13-Forbol
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Synonyms English:
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12,13-Dibutyrate, Phorbol
Phorbol 12,13 Dibutyrate
Phorbol-12,13-Dibutyrate
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Tree Number:
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D02.455.849.291.500.510.700
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Definition English:
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A phorbol ester found in CROTON OIL which, in addition to being a potent skin tumor promoter, is also an effective activator of calcium-activated, phospholipid-dependent protein kinase (protein kinase C). Due to its activation of this enzyme, phorbol 12,13-dibutyrate profoundly affects many different biological systems. |
Pharmacological Action:
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Carcinogens
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History Note English:
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89
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Allowable Qualifiers English:
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Record Number:
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23798
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Unique Identifier:
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D015240
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Occurrence in VHL:
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Similar:
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DeCS
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