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DeCS
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Descriptor English:
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MicroRNAs
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Descriptor Spanish:
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microARN
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Descriptor Portuguese:
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MicroRNAs
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Synonyms English:
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Micro RNA
MicroRNA
MicroRNA, Primary
Primary MicroRNA
Primary miRNA
RNA, Micro
RNA, Small Temporal
Small Temporal RNA
Temporal RNA, Small
miRNA
miRNA, Primary
miRNAs
pre miRNA
pre-miRNA
pri miRNA
pri-miRNA
stRNA
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Tree Number:
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D13.150.650.319
D13.444.735.150.319
D13.444.735.790.552.500
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Definition English:
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Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing. |
See Related English:
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RNA, Small Interfering
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History Note English:
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2003; use MICRORNAS (NM) 2001-2002
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Allowable Qualifiers English:
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Record Number:
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37535
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Unique Identifier:
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D035683
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Occurrence in VHL:
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Similar:
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DeCS
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