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SODIUM CHANNEL, PN3
Descriptors Found:
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DeCS
Descriptor
English
:
NAV1.8 Voltage-Gated Sodium Channel
Descriptor
Spanish
:
canales del sodio dependientes de voltaje NAV1.8
Descriptor
Portuguese
:
Canal de Sódio Disparado por Voltagem NAV1.8
Synonyms
English
:
NAV1.8 Voltage Gated Sodium Channel
PN3 Sodium Channel
Peripheral Nerve Sodium Channel 3
SCN10A Sodium Channel alpha Subunit
Sodium Channel Protein Type 10 Subunit alpha
Sodium Channel Protein Type X
Sodium Channel, PN3
Type 10 Voltage Gated Sodium Channel
Type 10 Voltage-Gated Sodium Channel
Voltage Gated Sodium Channel Type 10
Voltage Gated Sodium Channel Type 10 Subunit alpha
Voltage-Gated Sodium Channel Type 10
Voltage-Gated Sodium Channel Type 10 Subunit alpha
Tree Number:
D12.776.157.530.400.875.750.800
D12.776.543.550.450.875.750.800
D12.776.543.585.400.875.750.800
D12.776.631.960.800
Definition
English
:
A voltage-gated
sodium
channel subtype that is expressed in
nociceptors
, including spinal and trigeminal sensory
neurons
. It plays a role in the transmission of pain signals induced by cold, heat, and mechanical stimuli.
Entry Combination - descr/qualif
English
:
NAV1.8 Voltage-Gated Sodium Channel
/
antagonists & inhibitors
use
Voltage-Gated Sodium Channel Blockers
NAV1.8 Voltage-Gated Sodium Channel
/
agonists
use
Voltage-Gated Sodium Channel Agonists
History Note
English
:
2013
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54954
Unique Identifier:
D062559
Occurrence in VHL
:
Similar:
DeCS