Expresión de búsqueda:
MFN=57585
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Abciximab
Descriptor
Español
:
abciximab
Descriptor
Portugués
:
Abciximab
Sinónimos
Inglés
:
CentoRx
Chimeric 7E3 Fab
Clotinab
Fab, Chimeric 7E3
ReoPro
c7E3 Fab
Categoría:
D12.644.541.500.650.125
D12.776.124.486.485.114.224.060.125
D12.776.124.486.485.680.650.125
D12.776.124.790.651.114.224.060.125
D12.776.124.790.651.680.650.125
D12.776.377.715.548.114.224.200.125
D12.776.377.715.548.680.650.125
Definición
Inglés
:
A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks
PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX
, potently inhibiting
PLATELET AGGREGATION
. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in
patients
undergoing percutaneous coronary procedures such as
ANGIOPLASTY
;
ATHERECTOMY
; or stenting.
Acción Farmacológica:
Anticoagulants
Platelet Aggregation Inhibitors
Nota Histórica
Inglés
:
2019 (1994)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
57585
Identificador Único:
D000077284
Ocurrencia en la BVS
:
Similar:
DeCS