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DeCS
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Descriptor English:
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beta-Mannosidase
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Descriptor Spanish:
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beta-manosidasa
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Descriptor Portuguese:
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beta-Manosidase
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Synonyms English:
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beta D Mannosidase
beta Mannanase
beta Mannosidase
beta-D-Mannosidase
beta-Mannanase
manA protein (beta-Mannosidase)
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Tree Number:
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D08.811.277.450.625.750
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Definition English:
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An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS. |
Indexing Annotation English:
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/defic: consider also BETA-MANNOSIDOSIS
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See Related English:
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beta-Mannosidosis
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History Note English:
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2004; use BETA-MANNOSIDASE (NM) 1980-2003
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Allowable Qualifiers English:
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Record Number:
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38164
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Unique Identifier:
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D044902
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Occurrence in VHL:
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Similar:
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DeCS
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