Search on: ANKYRINS 
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Descriptor English:   Ankyrins 
Descriptor Spanish:   anquirinas 
Descriptor Portuguese:   Anquirinas 
Synonyms English:   Ankyrin  
Tree Number:   D12.776.543.080
Definition English:   A family of membrane-associated proteins responsible for the attachment of the cytoskeleton. Erythrocyte-related isoforms of ankyrin attach the SPECTRIN cytoskeleton to a transmembrane protein (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE) in the erythrocyte plasma membrane. Brain-related isoforms of ankyrin also exist. 
Indexing Annotation English:   membrane proteins; from the Greek word for anchor with ref to their role in attachment of the cytoskeleton; /drug eff /ultrastruct permitted
History Note English:   93; was ANKYRIN (NM) 1979-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30845 
Unique Identifier:   D017487 

Occurrence in VHL:
 

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